From glass chips to polymer chips: revolutionizing microfluidic technology

From glass chips to polymer chips: revolutionizing microfluidic technology

For many years, glass chips have been integral to biomedical applications, notably in microfluidic technology. However, recent advancements have illuminated that polymers offer comparable or even superior properties, alongside various other advantages. The transition towards polymers in microfluidics is fueled by several factors:

Cost: Polymers are generally more cost-effective than glass, crucial for applications requiring disposable or single-use devices.

Processability: Polymers are easier to process and manufacture into complex shapes and large quantities, enabling faster and scalable production of microfluidic devices.

Adequate optical transparency: Many polymers possess optical properties suitable for visual observation in microfluidic applications, such as microscopy.

Compatibility with mass production techniques: Polymers, particularly with processes like injection molding, facilitate large-scale production of microfluidic devices.

Biocompatibility: Polymers offer a wide range of biocompatible options, vital for interactions with living cells or biological tissues, promoting safer and more effective biomedical outcomes.

Moreover, comparing the features of glass and thermoplastic polymers in microfluidic applications:

Feature Glass Thermoplastic polymer
Cost High Low
Fabrication versatiliy Negative Moderate
Mechanical properties Good Good
Sterilization Positive Positive
Oxygen permeability Negative Variable

At Erreka Medical, we emphasize in the selection of the injected materials due to our high-quality manufacturing dedication. The most used thermopolymers are Cyclic Olefin Copolymer (COC) and Cyclic Olefin Polymer (COP) due to their outstanding attributes. With glass-like clarity, superior heat and chemical resistance, and superior purity, these materials exemplify our commitment to excellence in medical manufacturing.

In summary, the transition from glass to polymers in microfluidics is driven by considerations including cost-effectiveness, ease of fabrication, flexibility, optical transparency, biocompatibility, as well as thermal and chemical properties. This shift holds significant promise for advancing microfluidic technologies and enhancing biomedical applications.

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